She was done with the medication on Oct 31 and her hair was falling out and She started developing lymph nodes in her chest area. Then I searched it on the net & see all this stuff. The answer is yes, your dog can take Apoquel and Hydroxyzine together. Just like drugs for humans, they come with side effects and you have to weight out the benefit vs. the risks. In fact, antihistamines are quite often used to treat skin allergies in dogs. Full Year 2015 Guidance Updated to Revenue of $4.8 $4.9 Billion and Adjusted Diluted EPS1 of $1.61 $1.68 My dog had been on Prednisone several times before and he always had excessive urination but never had an accident in the house. THIS MED IS AWFUL & I SO WISHED I NEVER GAVE IT TO HIM!!!! P.S. I was too afraid so I gave her 1/2 dose and I thought she had a mild shake. What can you tell me? My Ginny was placed in ICU to help regulate her breathing. My vet bills have double. Liver counts are high is some areas so we will check again in two months. Due to her age, shes not the best at going outside, but on this pill, she is peeing constantly. Sounds like these side effevta most are coincidental. I even had to duct tape socks to his feet. People need to look at tbeir vetwhat has been tried first. Its use in cats, dogs, ferrets, horses, and birds to treat itchiness is 'off label' or 'extra label'. This affects how the drug works. She was still eating and seemed a little more tired so I wasnt alarmed. It worked almost immediately. My dog is so sick after two weeks of Apoquel neutrophil, eosinophil, and monocyte counts decreased among dogs in the oclacitinib group I just feel I needed to share these issues just in case anyone else has a pet that is suffering these same or similar symptoms. Has been on short term antibiotics and steroids for secondary skin infections. This drug works The treatment can be very effective. It worked right away and the itching was gone. After a few months the vet recommended Apoquel, we never thought to ask about side effects. I guess I need to do some more research. which is causing more messes to clean up. Janus kinase Inhibitors are on the market for the treatment of autoimmune diseases in humans including Xeljanz and baricitinib (Olumiant Lilly) for oral treatment of adults with moderately to severely active rheumatoid arthritis (RA). Cytopoint has worked wonderfully. Benadryl helps his runny nose and itchy eyes, but he was still scratching himself nonstop. I feel this is a very damaging drug with limited safety studies. He is a cocker spaniel who is now just over 10 years old. The Vitamin C dose is 100mg per 10lbs twice daily. WBC elevated, slight temperature, abdomen tender to touch and very dehydrated. I took my 58# It was attached to the muscle and she didnt cut into it because of the location of the tumor. Multiple doses of antibiotics for skin infections. Use the best of all forms of proven, safe and effective methods to find underlying causes and correct them. He was finished. We stopped Apoquel today because Alk phos is very high on last two tests. In simple terms, apoquel changes how the immune system acts. Apoquel is very dangerous. Treating dogs with antihistamines can take some trial and error as each animal reacts very differently. diarrhea, vomiting, and lethargy that resolved spontaneously in 90% of cases and did not He is about 3 yrs old. Sick part about it is I believe they make this drug for people too. Vet says its not from the Apoquel but I tend to disagree. My Vet said it looked cancerous when she aspirated it, does not mean that it is malignant but she did sound somewhat worried and talked about the way the nuclei looked under the microscope. Any suggestions for options other than what I have already tried, in order to get him off Apoquel? Not sure it will make a difference or if they even care, but I hope this message will bring hope to others who are currently experiencing the downside to Apoquel. But, I did notice your office carried CET chews, Metacam, and Baytril. In addition to Allergies Atopy, and acute, short-term condition or can be recurrent or chronicall which can impact the Its nice to see her not so stressed out over scratching and with a beauriful full coat. Do not use in breeding, pregnant, or nursing dogs. Bit worried my E.R. The Vet eventually suggested Apoquel. petrified! Horrible diarrhea that even woke me up because she was frantic to get out in the middle of the nightalong with accidents of that nature, as well as the pee in the back bedroom.. (thank goodness we have hardwood floors). Gave this med to my 9 year old Rat Terrier.. now she is dead. How long does it take for gabapentin to kick in for dogs? I saw your interview, where you complained people werent being told about the side effects of medications. I knew nothing about Apoquels side effects until I saw their commercial a couple of months ago where it states a lot of bad things that can happen to your pet including making cancer grow MUCH faster. I would have preferred using prednisone as it has worked well in the past and he didnt need to take much. Reading the experiences above, I now figure that his stomach is upset. And one last comment, you claim that Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. We will know more next week when the report comes back from histopatholgy. Out of desperation I took both dogs off of Apoquell and within one day started noting improvement in behavior but he still was shaking with fear and very susceptible to noise. My supplement, Ultimate Canine Health Formula contains bovine colostrum in adequate levels for your dog. She slept on my bed and had since she was 10 weeks. I certainly want her to be happy but also healthy. Nothing can bring back my Ginny, she is gone ;( please please do not give Apoquel to your fur baby. I watch the Zeljanz commercial which is basically a very similar drug for humans.listening to all the huge long list of potential side effects.cancers have happened and they say it like potential for thunderstormslike no big deal. I called the vet but they said she must have eaten something to cause it. He is obviously off the medicine and on new medicine to help his liver until the extent of the damage is assessed and the Dr. can provide a treatment plan moving forward. So, our story is our 7 mo. No, I dont think I will give it to him again. I dont think so.. dont use this drug! Dogs with the MDR1 genetic mutation can become very ill or die if given certain medications. The study she pulled said 10% of dogs will develop these tumors with Apoquel. Im convinced its from this med!!! It makes me sick to my stomach to see so many vets pushing and advertising this. I was considering Apoquel for my 8 year old German Shepherd. Im on this site after its too late. Hi. I dont have the answers but please think about comments before you write them. The safety and efficacy of Apoquel has not been evaluated in humans, and it is not recommended for use in people. Atopic dermatitis is one of the most common allergies in dogs, affecting approximately Had my dog on this for about a month. Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. Apoquel should be given orally to your dog as a pill twice daily for the first 14 days, then reduced to once daily for maintenance. They can help calm the patient when itching and discomfort cause distress. Hello, I have 2 german shepherds. Ive taken her to the vet 4 times in less than 2 weeks. The vet prescribed it and at first her allergies were better. You can use a Natural flea spray that has cedarwood oil, and a safe holistic powder for putting in the cracks and crevices of your house called Borax. I am seriously thinking this drug is to blame. The other option would have probably would have been a lot worse. Last two days he has been down barely able to raise his head and not walking at all. Does anyone else experience these symptoms? Since it is a short-acting drug, the effects will be gone in 24 hours; however, the medication may last longer in dogs with renal or liver impairment. Some dogs taking other types of antihistamines have also experienced vomiting. I have read your comments about your pets having side effects. She was a stray and was having such allergies I finally decided to get her an allergy panel. Was just told it was better then puting him on prednisone because it wouldnt cause the aggression. My dog is much worse now and has a tumor under her forearm. He actually unlocked a sliding glass door aggressively scratching at the walls and door jam and got out and was digging under the fence when our neighbor whom we called came and put him back in the house. Your vet may prescribe it to relieve the symptoms of an allergic reaction. Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. She sounds like a very sweet dog not making a mess for you. My vet is concerned that anything she gives him will result in his pancreatitis flaring up so she has told me to give him Benadryl and we have an appt to see a dermatologist in a few days. 4 years ago when we brought her home we noticed her always itching, mostly her ears and biting her feet. It was gradual, but now after seven days off the Apoquel, he is back to his normal self. But I dont know if 30 days is enough. Anyway hes now almost bald (his allergies have been that bad) I have also found another lump on his back leg. We thought we were going to lose her. Some of the horror stories above are frightening. Go ahead with apoquel. Puppy was briefly having loose stool and some vomiting cleared up w/Flagyl- metronizone. At the beginning of Spring of this year. Apoquel has made my dog awfully ill. We have spent so much money from the side effects of apoquel. of the development of severe pyoderma (after day 19) and one dog withdrew because of the Apoquel is safe to use in dogs one year and older. The veterinarian removed the cysts with Aries requiring to stay overnight under observation. Topical Solutions Use a topical product that works to calm the source of the itchy skin and inflammation. The active ingredient in this medication is called oclacitinib. I thought I had found the magic drug. Available dosages: Tablets = 2 mg, 4 mg, and 8 mg; Extended-Release Tablets = 12 mg; Syrup = 0.4 mg/mL. It started as seasonal allergies but he ended up itching all year round. Everything looked fine but her liver enzymes were elevated. Thanks to all for yoru comments. But because he was itching excessively, the Vet prescribed Apoquel. I wouldnt recommend it after our issues with it and reading others comments. Hi I would get a blood panel done. My advice, such as it is, is to inform yourself as much as you can about anything that you are going to give your dog and watch them closely while on it. I am having the same issue as Kelly noted above. Im conflicted now that I might have caused this. My son just lost his beautiful 3 year old Dalmatian to the drug. Be aware that some antihistamines can cause drowsiness. Told vet and she took bloods so fingers crossed. Allergies2 months ago prescribed Apoquel. I am very upset. I took him to my vet who then sent me to Emergency. What drugs should not be taken with Apoquel? She has had none of the issues above. Apoquel can be given with or without food. How long can a dog take Apoquel? can respond inappropriately, and may begin attacking the dog? She began taking it in Nov. Of 2019. This is not like him.So I am going to quit giving him this med. Another prescription for Apoquel 5.4mg 70 tablets were dispensed to us for $126.00 We again returned to the center on April 30, 2018 to evaluate but left only with another prescription for Apoquel for $138.60. My dog had a history of pancreatitis, vet should have known this product and think this is not good for this dog. But, we are seeing improvementfinally. It was under the skin, wide but flat so it didnt show under his hair and wasnt obvious when patting him. Im anxious to see what happens. require discontinuation of therapy. Cytopoint is an, on average, once a month injection into the skin. Yes I know Bulls are prone to skin allergies so I thought this Apoquel was finally the answer. If your dog vomits after taking Apoquel , try giving it with some food or a meal after consulting with your vet. Fourth Quarter 2014 Adjusted Net Income of $203 Million, or Adjusted Diluted EPS1 He was a totally healthy dog before Apoquel! I have many questions, and was wondering does anyone who has had similar issues with apoquel know how long this nightmare of a drug stays in a dogs system. Our veterinarian prescribed Apoquel on my doggie and she killed him. I came online tonight to look for someplace to buy this drug cheaper than the 78.00 a month I was getting from the vet.MY shepherd border collie has had it for a month and did wonderful with no side effects besides needing more fluids thus more potty breaks. The last time I had her back on it she has had severe nausea at night and trembling. Last June 2016 our vet prescribed Apoquel for our 8 year old Shih Tzu for her itching. Apoquel Dosage. My 5 year old,Lab/Bassett mix, was on Apoquel,the wonder drug. She has been on it for about 3 weeks now. I used some anti inflammation drops I had left over from dermatology vet and they seemed to be working but it is short lived and the yeast is still there. Along with this, came the increased urination. She had 10 seizures in 3 months. So, does Apoquel stop itching? The sedative properties are beneficial in these instances. In his 10 years he has never defecated in the house. As another poster mentioned she was panting, in pain and suffering. My dog was on Apoquel for several months. I hate to have my sweet condfidant puppy be scared of his own shadow but at the same time hes super happy and playful to not be so itchy! Reason for delay: Vets have killed two of my pets very painfully and believe that the prior vets medication killed this one. After 3 days she is back to scratching, licking and bighting again with enflamed skin and a lot less energy. was up all night with the poor little guy, he was panicking badly, jumping into my lap, whimpering, panting,he was doing a weird head stretch thing ,could not settle, drinking loads stopped the apoquel,took him to emergency vet, had bloods etc checked & they said he was fine. Read about the JAK inhibitors that protect your dog from developing immune diseases, these inhibitors PROTECT your dog, this drug turns them off. I ended up at the emergency hospital where he was put on antibiotics, IVs and had X-rays, bloods and ultrasounds done. Apoquel Side Effects. Can you give a dog Apoquel and Benadryl at the same time? I do not know what to think at this point and Im upset I didnt know the long term side effects of this miracle drug could possibly be responsible for the sickness of my dog. I pray my dog They assumed that he must have a tumor, so, we scheduled an Ultrasound. I certainly dont want to cause the side effects that I read. We put my boy on it and yes, it did work great. It stopped the itching immediately and he was finally able to get relief. Today we was at the vets, my Westie mix bison was given Apoquel 5.6grm and I gave him one today,after reading all your comments. These days, another type known as H2 antihistamines are commonly used. If anyone has experienced this side effect and has any additional information I would greatly appreciate the knowledge. It may be used off label to treat skin infections in cats and urinary tract infections in dogs. Low numbers of dogs in the studies developed demodicosis, neoplasia, pneumonia, bloody diarrhea, skin and ear infections . Ive been searching all day and came across other dogs doing the same. They have only been on the drug for two weeks but when my husband petted Hamish he noticed a massive lump on his chest. Despite providing the vet center with a copy of my letter to Zoetis and their request to have the vet contact them to discuss this AE, as of 9-6-19 the vet has not contacted them. I would hate to think that the profit that vets make from exclusively distributing Apoquel out shines their professional duty to be appear of these serious adverse events especially given my case where the veterinarian started prescribing Apoquel in December 2016 and started to see these parasitic growths appear within 3 months of initiation of therapy. The dog lost 10 pounds and recovered from the UTI but the previous cancer returned and she become seriously ill very quickly and we lost our beautiful dog. I found a Veterinarian that was also a Herbalist. Please listen to Dr. Jones. His nose is cold and his behavior is normal, but we are very worried. But lately the allergic reaction has gotten worse and I have spent a small fortune at the vet. Last spring, his scratching caused the side of his face to look like he had been attacked and lost the fight. He now has lumps on his thighs and side under his skin. You may stop using medications all together. I do not believe there was enough testing done on this drug. It's . The vitamins actually made him strong not to get the seasonal allergies so bad. I think if you are caught up on the FDA trial studies, please look at every drugs FDA trials. We all need to do our part to get this drug off the market. Then came the motor coordination hiccups. my newfie takes 1 1/2 tabs. Of those 247 dogs, they removed 26 dogs from the study for one reason or another and 18 were euthanized. In some cases, more serious side effects may occur, such as infections or tumors. We inquired on several occasions if Apoquell would have caused all of this and were reassured it would not. Also of note, this drug is not labeled for cats. My vet put my 2year old French Bulldog on this med last week for constant paw licking as piriton wasnt giving him much relief 1st day my whole family said He was acting odd later that night it seemed like he was seeing & sensing things that werent there on the 2nd day he was becoming a bit nervous & also lifting his back paw like he was in discomfort that night he was like completely spooked! Strange about aggression as a side effect could it be she just doesnt feel good on the drug and irritable? It works perfectly, but it takes a little while before it knocks everything out. It has a different mechanism of action than steroids, cyclosporine, antihistamines, allergy shots and sublingual immunotherapy. A small study of 299 dogs- 50% of the dogs took the placebo medication, and most dropped out of the study. She was refusing to eat out of her bowl which was a red flag because our cocker spaniel is OBSESSEd with food ( I think she likes food more than she likes us ?). I wish I had researched this forum before. The most common application of hydroxyzine for dogs is in relation to the treatment of pruritus. I have found others not just on this web site that are questioning the same thing. This weekend, she developed diarrhea. After reading almost all of the comments on here I would think you would all exchange info and file a Class Action Lawsuit against the makers of this drug, the FDA for negligence, at least. Does zonisamide interact with my other drugs? Thanks for your advise earlier about the beta 3. This again required an overnight stay at the vet center with a total cost of $2452.23 It was like a miracle drug. I searched apparel and found that this was a side affect. I guess I need to do some more research vet who then sent to... Very painfully and believe that the prior vets medication killed this one allergy panel ) I have found others just!, this drug is to blame to see so many vets pushing and this... 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